Brain Cancer


1. Bromelain Reversibly Inhibits Invasive Properties of Glioma Cells


1. Investigating the therapeutic role and molecular biology of curcumin as a treatment for glioblastoma

2. Curcumin suppresses cell growth and invasion and induces apoptosis by down-regulation of Skp2 pathway in glioma cells

Epigallocatechingallate (EGCG)

1. Epigallocatechin-3-gallate induces apoptosis and proliferation inhibition of glioma cell through suppressing JAK2/STAT3 signaling pathway

2. Green Tea polyphenol (-)-epigallocatechin-3-gallate inhibits MMP-2 secretion and MT1-MMP-driven migration in glioblastoma cells


1. Enhancing the anti-glioma therapy of doxorubicin by honokiol with biodegradable self-assembling micelles through multiple evaluations

2. Magnolol and honokiol exert a synergistic anti-tumor effect through autophagy and apoptosis in human glioblastomas

3. Honokiol-induced apoptosis and autophagy in glioblastoma multiforme cells

4. Elimination of Cancer Stem-Like Cells and Potentiation of Temozolomide Sensitivity by Honokiol in Glioblastoma Multiforme Cells

5. Honokiol traverses the blood-brain barrier and induces apoptosis of neuroblastoma cells via an intrinsic bax-mitochondrion-cytochrome c-caspase protease pathway

6. Honokiol Crosses BBB and BCSFB, and Inhibits BrainTumor Growth in Rat 9L Intracerebral Gliosarcoma Model and Human U251 Xenograft Glioma Model


1. Application of luteolin nanomicelles anti-glioma effect with improvement in vitro and in vivo

2. Luteolin reduces migration of human glioblastoma cell lines via inhibition of the p-IGF 1R/PI3K/AKT/mTOR signaling pathway

3. Biphasic effects of luteolin on interleukin-1β-induced cyclooxygenase-2 expression in glioblastoma cells

4. Luteolin inhibits migration of human glioblastoma U-87 MG and T98G cells through downregulation of Cdc42 expression and PI3K/AKT activity

Panax ginseng

1. GinsenosideRh2 inhibits human A172 glioma cell proliferation and induces cell cycle arrest status via modulating Akt signaling pathway

2. Anti-Cancer Effect of Ginsenoside F2 against Glioblastoma Multiforme in Xenograft Model in SD Rats


1. Resveratrol Impairs Glioma Stem Cells Proliferation and Motility by Modulating the Wnt Signaling Pathway

2. Resveratrol inhibits glioma cell growth via targeting oncogenic microRNAs and multiple signaling pathways

3. Resveratrol and quercetin cooperate to induce senescence-like growth arrest in C6 rat glioma cells

4. Inhibition of STAT3Expression and Signaling in Resveratrol-Differentiated Medulloblastoma Cells

Tinospora cordifolia

1. Aqueous Ethanolic Extract of Tinospora cordifolia as a Potential Candidate for Differentiation Based Therapy of Glioblastomas

Vitamin C

1. High Dose Ascorbate Causes Both Genotoxic and Metabolic Stress in Glioma Cells

2. The Effect of Ascorbic Acid over the Etoposide- and Temozolomide-Mediated Cytotoxicity in Glioblastoma Cell Culture: A Molecular Study/a>

3. High-Dose Intravenous Vitamin C Treatment of a Child with Neurofibromatosis Type 1 and Optic Pathway Glioma: A Case Report

4. Superoxide-dependent uptake of vitamin C in human glioma cells