Liver Cancer

Epigallocatechingallate (EGCG)

1. Green Tea Polyphenol, Epigallocatechin- 3-Gallate (EGCG): Mechanisms and Application on Hepatocellular Carcinoma

2. Epigallocatechin-3 gallate induces the apoptosis of hepatocellular carcinoma LM6 cells but not non cancerous liver cells


1. Non-toxic dose of liposomal honokiol suppresses metastasis of hepatocellular carcinoma through destabilizing EGFR and inhibiting the downstream pathways

2. Combined effect of honokiol and rosiglitazone on cell growth inhibition through enhanced G0/G1 phase arrest in hepatoma cells

3. Growth Inhibitory Activity of Honokiol through Cell-cycle Arrest, Apoptosis and Suppression of Akt/mTOR Signaling in Human Hepatocellular Carcinoma Cells


1. Effect of Genistein on Apoptosis and Proliferation of Hepatocellular Carcinoma Hepa1‑6 Cell Line

2. Isoflavones-Enriched Soy Protein Prevents CCL4-InducedHepatotoxicity in Rats

3. Inhibitory Effect of Genistein on PLC/PRF5 Hepatocellular Carcinoma Cell Line

4. Plasma Isoflavones and Risk of Primary Liver Cancer in Japanese Women and Men with Hepatitis Virus Infection: A Nested Case–Control Study

5. Effect of Genistein and 17‑β Estradiol on the Viability and Apoptosis of Human Hepatocellular Carcinoma HepG2 cell line

6. Isoflavone consumption and subsequent risk of hepatocellular carcinoma in a population-based prospective cohort of Japanese men and women


1. Luteolin Promotes Cell Apoptosis by Inducing Autophagy in Hepatocellular Carcinoma

2. Luteolin induces apoptosis in mouse liver cancer cells through ROS mediated pathway: A mechanistic investigation

3. Luteolin and sorafenib combination kills human hepatocellular carcinoma cells through apoptosis potentiation and JNK activation

4. Evaluation of Luteolin in the Prevention of N-nitrosodiethylamine-induced Hepatocellular Carcinoma Using Animal Model System

Morinda citrifolia (Noni)

In Vitro


2. Damnacanthal, a noni anthraquinone, inhibits c-Met and is a potent antitumor compound against Hep G2 human hepatocellular carcinoma cells

3. Studies on anticancer activity of ethanolic extract of Noni fruit (Morinda citrifolia L.)

In Vivo

1. Hepatoprotective effects of naturally fermented noni juice against thioacetamide-induced liver fibrosis in rats

2. Liver Protective Effects of Morinda citrifolia (Noni)

3. Anti-fibrotic effect of Noni (Morinda citrifolia L.) on carbon tetrachloride liver fibrosis

Panax ginseng

1. GinsenosideRh2 inhibits hepatocellular carcinoma through β-catenin and autophagy

2. GinsenosideRg3 attenuates hepatoma VEGF overexpression after hepatic artery embolization in an orthotopic transplantation hepatocellular carcinoma rat model

3. 20(S)-Ginsenoside Rg3 is a novel inhibitor of autophagy and sensitizes hepatocellular carcinoma to doxorubicin

4. Korean Ginseng Suppresses Metastasis of Human HepatomaSK-Hep1Cells by InhibitingMatrixMetalloproteinase-2/-9 and Urokinase Plasminogen Activator

5. Autophagy Inhibition Enhances Apoptosis Induced by Ginsenoside Rk1 in Hepatocellular Carcinoma Cells


1. Probiotics modulated gut microbiota suppresses hepatocellular carcinoma growth in mice

2. Gut Microbiota and Hepatocellular Carcinoma

3. Effect of Probiotics on Liver Function After Surgery Resection for Malignancy in the Liver Cirrhotic


In Vitro

1. Novel combination of thymoquinone and resveratrol enhances anticancer effect on hepatocellular carcinoma cell line

2. Resveratrol inhibits proliferation and migration through SIRT1 mediated post translational modification of PI3K/AKT signaling in hepatocellular carcinoma cells

3. Resveratrol enhances anticancer effects of paclitaxel in HepG2 human liver cancer cells

4. Resveratrol suppresses human hepatocellular carcinoma via targeting HGF-c-Met signaling pathway

5. Potentiation of resveratrol-induced apoptosis by matrine in human hepatoma HepG2 cells

6. Synergistic anticancer effects of curcumin and resveratrol in Hepa1-6 hepatocellular carcinoma cells

7. The Antimetastatic Effects of Resveratrol on Hepatocellular Carcinoma through the Downregulation of a Metastasis-Associated Protease by SP-1 Modulation

8. Resveratrol Induces Apoptosis in Human SK-HEP-1 Hepatic Cancer Cells

9. Anti-hepatoma activity of resveratrol in vitro

In Vivo

1. The Role of Resveratrol in Cancer Therapy

2. Influence of resveratrol on liver fibrosis induced by dimethylnitrosamine in male rats

3. Resveratrol suppresses human hepatocellular carcinoma via targeting HGF-c-Met signaling pathway

4. Anticancer properties of resveratrol on chemically induced hepatocellular carcinoma in rats: Inhibition of metastasis and angiogenesis

5. By reducing hexokinase 2, resveratrol induces apoptosis in HCC cells addicted to aerobic glycolysis and inhibits tumor growth in mice

6. Resveratrol and cancer: focus on in vivo evidence

7. Resveratrol and liver: A systematic review

8. Chemoprevention of HBV-related hepatocellular carcinoma by the combined product of resveratrol and silymarin in transgenic mice

9. Resveratrol Downregulates Cyp2e1 and Attenuates Chemically Induced Hepatocarcinogenesis in SD Rats

10. Resveratrol Helps Recovery from Fatty Liver and Protects against Hepatocellular Carcinoma Induced by Hepatitis B Virus X Protein in a Mouse Model

11. Angioprevention is Implicated in Resveratrol Chemoprevention of Experimental Hepatocarcinogenesis

12. Resveratrol Suppresses Oxidative Stress and Inflammatory Response in Diethylnitrosamine-Initiated Rat Hepatocarcinogenesis

Spirulina platensis

1. Chemoprevention of rat liver toxicity and carcinogenesis by Spirulina

Vitamin C

1. Vitamin C preferentially kills cancer stem cells in hepatocellular carcinoma via SVCT-2

2. Vitamin C enhances anticancer activity in methotrexate treated Hep3B hepatocellular carcinoma cells

3. Effects of ascorbic acid and b-carotene on HepG2 human hepatocellular carcinoma cell line