Anti-cancer Activities of Probiotics

1. Gut Microbiota and Cancer: From Pathogenesis to Therapy

2. Probiotics in the Treatment of Colorectal Cancer

3. Human Gut Microbiota and Gastrointestinal Cancer

4. Pre-, pro- and synbiotics in cancer prevention and treatment—a review of basic and clinical research

5. Probiotics and their role in gastrointestinal cancers prevention and treatment; an overview

6. Dysbiosis of gut microbiota in promoting the development of colorectal cancer

7. Review of the mechanisms of probiotic actions in the prevention of colorectal cancer

8. The Role of Probiotics in Cancer Treatment: Emphasis on their In Vivo and In Vitro Anti-metastatic Effects

9. Metabiotics: One Step ahead of Probiotics; an Insight into Mechanisms Involved in Anticancerous Effect in Colorectal Cancer

10. Anti-Cancer Properties of Probiotics: A Natural Strategy for Cancer Prevention

11. Colon Cancer Prevention through Probiotics: An Overview

12. Potential role of probiotics on colorectal cancer Prevention

13. The intestinal microbiota, gastrointestinal environment and colorectal cancer: a putative role for probiotics in prevention of colorectal cancer?

14. Cancer Chemopreventive Effects of Lactic Acid Bacteria

15. Lactic acid bacteria and cancer: mechanistic perspective


Colorectal Cancer

In Vitro

1. Exopolysaccharides produced by Lactobacillus strains suppress HT‑29 cell growth via induction of G0/G1 cell cycle arrest and apoptosis

2. Antiproliferative effects on colon adenocarcinoma cells induced by co-administration of vitamin K1and Lactobacillus rhamnosus GG

3. Dual Anti-Metastatic and Anti-Proliferative Activity Assessment of Two Probiotics on HeLa and HT-29 Cell Lines

4. Effects of Probiotic Lactobacillus acidophilus and Lactobacillus casei on Colorectal Tumor Cells Activity (CaCo-2)

5. Antiproliferative and Proapoptotic Effects of Viable or Heat-Killed Lactobacillus paracasei1 and Lactobacillus rhamnosus GG in HGC-27 Gastric and DLD-1 Colon Cell Lines

6. Probiotic Lactobacillus Acidophilus and Casei Mix Sensitize Colorectal Tumoral Cells to 5-Fluorouracil-Induced Apoptosis

In Vivo

1. Synbiotics suppress colitis-induced tumorigenesis in a colon-specific cancer mouse model

2. Microbiota modification by probiotic supplementation reduces colitis associated colon cancer in mice

3. Lactobacillus casei Variety rhamnosus Probiotic Preventively Attenuates 5-Fluorouracil/ Oxaliplatin-Induced Intestinal Injury in a Syngeneic Colorectal Cancer Model

4. Prophylactic intervention of probiotics (acidophilus, L.rhamnosus GG) and celecoxib modulate Bax-mediated apoptosis in 1,2-dimethylhydrazine-induced experimental colon carcinogenesis

5. Probiotic Strain Lactobacillus casei BL23 Prevents Colitis-Associated Colorectal Cancer

6. Lactobacillus casei Zhang and vitamin K2 prevent intestinal tumorigenesis in mice via adiponectin-elevated different signaling pathways

7. Lactobacillus casei Exerts Anti-Proliferative Effects Accompanied by Apoptotic Cell Death and Up-Regulation of TRAIL in Colon Carcinoma Cells

8. Probiotic-derived ferrichrome inhibits colon cancer progression via JNK-mediated apoptosis

9. Protective Effects of Probiotic Lactobacillus rhamnosus IMC501 in Mice Treated with PhIP

10. Probiotics Lactobacillus rhamnosus GG, Lactobacillus acidophilus Suppresses DMH-Induced Procarcinogenic Fecal Enzymes and Preneoplastic Aberrant Crypt Foci in Early Colon Carcinogenesis in Sprague Dawley Rats


Clinical Trials of Lactobacillus caesi and L. rhamnosus

1. Probiotics and Colon Cancer

2. Benefits of using probiotics as adjuvants in anticancer therapy (Review)

3. A randomized double-blind placebo controlled trial of probiotics in post-surgical colorectal cancer

4. Probiotics as a preventive strategy for surgical infection in colorectal cancer patients: a systematic review and meta-analysis of randomized trials

5. Synbiotics and gastrointestinal function-related quality of life after elective colorectal cancer resection

6. Emerging roles of lactic acid bacteria in protection against colorectal cancer

7. Probiotics in colorectal cancer (CRC) with emphasis on mechanisms of action and current perspectives

8. Probiotics as efficient immunopotentiators: Translational role in cancer prevention

9. Lactobacillus supplementation for diarrhoea related to chemotherapy of colorectal cancer: a randomised study

10. Randomized trial of dietary fiber and Lactobacillus casei administration for prevention of colorectal tumors