Stomach Cancer

Bromelain

1.Potentiation of chemotherapeutics by bromelain and N-acetylcysteine: sequential and combination therapy of gastrointestinal cancer cells

2.Depletion of mucin in mucin-producing human gastrointestinal carcinoma: Results from in vitro and in vivo studies with bromelain and N-acetylcysteine

3.Bromelain and N-acetylcysteine inhibit proliferation and survival of gastrointestinal cancer cells in vitro: significance of combination therapy

4.Anti-tumour and Chemosensitising Effect of a Combination of Bromelain+ N-Acetyl Cysteine with Cisplatin or 5-Fu on Malignant Peritoneal Mesothelioma Cells

5.Cytotoxic effects of bromelain in human gastrointestinal carcinoma cell lines (MKN45, KATO-III, HT29-5F12, and HT29-5M21)

Carotenoids

1.Vitamin A, retinol, and carotenoids and the risk of gastric cancer: a prospective cohort study

Curcumin

In Vitro

1.Curcumin suppresses gastric cancer by inhibiting gastrin-mediated acid secretion

2.Curcumin suppresses gastric tumor cell growth via ROS-mediated DNA polymerase γ depletion disrupting cellular bioenergetics

3.Enhancing Effects of Curcumin on Cytotoxicity of Paclitaxel, Methotrexate and Vincristine in Gastric Cancer Cells

4.Strategy to enhance efficacy of doxorubicin by curcumin as a potent Pgp inhibitor in gastric cancer

5.Curcumin sensitizes human gastric cancer cells to 5-fluorouracil through inhibition of the NFκB survival-signaling pathway

6.Combinational Treatment of Curcumin and Quercetin against Gastric Cancer MGC-803 Cells in Vitro

7.Curcumin suppresses the proliferation of gastric cancer cells by downregulating H19

8.Synergistic anticancer effect of curcumin and chemotherapy regimen FP in human gastric cancer MGC 803 cells

9.Curcumin inhibits proliferation of gastric cancer cells by impairing ATP-sensitive potassium channel opening

10.Curcumin reverses chemoresistance of human gastric cancer cells by downregulating the NF-κB transcription factor

11.Curcumin suppresses proliferation and invasion in human gastric cancer cells by down-regulation of PAK1 activity and cyclin D1 expression

In Vivo

1.Curcumin Enhances the Anticancer Effect Of 5-fluorouracil against Gastric Cancer through Down-Regulation of COX-2 and NF- κB Signaling Pathways

2.pH Triggered Curcumin Release from PMMA-AA Coated ZnO Nanoparticles for Excellent Anti-Gastric Cancer Therapy

3.Curcumin Enhances the Effects of 5-Fluorouracil and Oxaliplatin in Inducing Gastric Cancer Cell Apoptosis Both In Vitro and In Vivo

4.Curcumin Attenuates Gastric Cancer Induced by N-Methyl-N-Nitrosourea and Saturated Sodium Chloride in Rats

Clinical Trial

1.Therapeutic Roles of Curcumin: Lessons Learned from Clinical Trials

Epigallocatechingallate (EGCG)

1.Regulation of Id1expression by epigallocatechin 3 gallate and its effect on the proliferation and apoptosis of poorly differentiated AGS gastric cancer cells

2.(-)-Epigallocatechin-3-gallate inhibits growth of gastric cancer by reducing VGEF production and angiogenesis

Honokiol

1.Honokiol induces cell cycle arrest and apoptosis in human gastric carcinoma MGC-803 cell line

2.Honokiol thwarts gastric tumor growth and peritoneal dissemination by inhibiting Tpl2 in an orthotopic model

3.Calpain/SHP-1 Interaction by Honokiol Dampening Peritoneal Dissemination of Gastric Cancer in nu/nu Mice

4.Honokiol Induces Calpain-Mediated Glucose-RegulatedProtein-94 Cleavage and Apoptosis in Human Gastric Cancer Cells and Reduces Tumor Growth

Isoflavones

1.The association between dietary isoflavones intake and gastric cancer risk: a meta-analysis of epidemiological studies

2.Dietary isoflavones and gastric cancer: A brief review of current studies

3.Soy isoflavone intake and stomach cancer risk in Japan: From the Takayama study

4.Isoflavone intake and risk of gastric cancer: a population-based prospective cohort study in Japan

5.Isoflavones from Phytoestrogens and Gastric Cancer Risk: A Nested Case-Control Study within the Korean Multicenter Cancer Cohort

Luteolin

1.Luteolin selectively kills STAT3 highly activated gastric cancer cells through enhancing the binding of STAT3 toSHP-1

2.Luteolin suppresses gastric cancer progression by reversing epithelial ‑mesenchymal transition via suppression of the Notch signaling pathway

3.Luteolin exerts a marked antitumor effect incMet-overexpressing patient-derived tumor xenograft models of gastric cancer

Lycopene

1.Anticancer Effect of Lycopene in Gastric Carcinogenesis

Panax ginseng

1.An enzymatically fortified ginseng extract inhibits proliferation and induces apoptosis of KATO3 human gastric cancer cells via modulation of Bax, mTOR, PKB and IκBα

2.Stereospecific anticancer effects of ginsenoside Rg3 epimers isolated from heat-processed American ginseng on human gastric cancer cell

3.Ginseng Intake and Gastric Cancer Risk in the Shanghai Women’s Health Study Cohort

Probiotics

1.Human Gut Microbiota and Gastrointestinal Cancer

2.Effect of probiotics on small intestinal bacterial overgrowth in patients with gastric and colorectal cancer

3.Lactobacillus casei Extract Induces Apoptosis in Gastric Cancer by Inhibiting NF-κB and mTOR-Mediated Signaling

Quercetin

1.Quercetin Has Antimetastatic Effects on Gastric Cancer Cells via the Interruption of uPA/uPAR Function by Modulating NF-κb, PKC-δ, ERK1/2, and AMPKα

2.Dietary quercetin intake and risk of gastric cancer: results from a population based study in Sweden

3.Quercetin induces protective autophagy in gastric cancer cells

Resveratrol

In Vitro

1.Mediation of the Anticancer Effects of Resveratrol via the Upregulation of Tristetraprolin in Gastric Cancer Cell

2.Expression of genes and proteins of multidrug resistance in gastric cancer cells treated with resveratrol

3.Resveratrol induces apoptosis in SGC 7901 gastric cancer cells

4.Resveratrol inhibits the growth of gastric cancer via the Wnt/β-catenin pathway

5.Resveratrol reverses Doxorubicin resistance by inhibiting epithelial-mesenchymal transition (EMT) through modulating PTEN/Akt signaling pathway in gastric cancer

6.Resveratrol induces cell cycle arrest in human gastric cancer MGC803 cells via the PTEN-regulated PI3K/Akt signaling pathway

7.Effects of resveratrol on the protein expression of survivin and cell apoptosis in human gastric cancer cells

8.Inhibition of Sphingolipid Metabolism Enhances Resveratrol Chemotherapy in Human Gastric Cancer Cells

9.The genotoxicity study of resveratrol in primary gastric adenocarcinoma cell cultures

10.Inhibition of gastric cancer cell proliferation by resveratrol: role of nitric oxide

In Vivo

1.Resveratrol reverses Doxorubicin resistance by inhibiting epithelial-mesenchymal transition (EMT) through modulating PTEN/Akt signaling pathway in gastric cancer

2.Resveratrol: A potential challenger against gastric cancer

3.Resveratrol Inhibits the Growth of Gastric Cancer by Inducing G1 Phase Arrest and Senescence in a Sirt1-Dependent Manner

Vitamin C

1.Pharmacological Ascorbate Suppresses Growth of Gastric Cancer Cells with GLUT1 Overexpression and Enhances the Efficacy of Oxaliplatin Through Redox Modulation

2.Study of Serum Vitamin-C levels in Carcinoma Stomach

3.Mechanism of Ascorbic Acid-induced Reversion Against Malignant Phenotype in Human Gastric Cancer Cells

4.Effect of physiological concentrations of vitamin C on gastric cancer cells and Helicobacter pylori

5.Ascorbic acid and intestinal metaplasia in the stomach: a prospective, randomized study