Bone Cancer

1. The flavonoid luteolin enhances doxorubicin-induced autophagy in human osteosarcoma U2OS cells

2. Molecular Mechanisms of Luteolin Induced Growth Inhibition and Apoptosis of Human Osteosarcoma Cells

Brain Cancer

1. Application of luteolin nanomicelles anti-glioma effect with improvement in vitro and in vivo

2. Luteolin reduces migration of human glioblastoma cell lines via inhibition of the p-IGF 1R/PI3K/AKT/mTOR signaling pathway

3. Biphasic effects of luteolin on interleukin-1β-induced cyclooxygenase-2 expression in glioblastoma cells

4. Luteolin inhibits migration of human glioblastoma U-87 MG and T98G cells through downregulation of Cdc42 expression and PI3K/AKT activity

Breast Cancer

1. Luteolin inhibits lung metastasis, cell migration, and viability of triple-negative breast cancer cells

2. Luteolin Inhibits Breast Cancer Development and Progression In Vitro and In Vivo by Suppressing Notch Signaling and Regulating MiRNAs

3. Luteolin inhibits progestin‑dependent angiogenesis, stem cell‑like characteristics, and growth of human breast cancer xenografts

4. Flavones inhibit breast cancer proliferation through the Akt/FOXO3a signaling Pathway

5. Synergistic apoptotic effect of celecoxib and luteolin on breast cancer cells

Colorectal Cancer

1. Combination of oncolytic adenovirus and luteolin exerts synergistic antitumor effects in colorectal cancer cells and a mouse model

2. Modulation of G2/M cell cycle arrest and apoptosis by luteolin in human colon cancer cells and xenografts

3. Luteolin, a Bioflavonoid Inhibits Colorectal Cancer through Modulation of Multiple Signaling Pathways: A Review

4. Cytotoxic Effect of Luteolin on Human Colorectal Cancer Cell Line (HCT-15): Crucial Involvement of Reactive Oxygen Species

5. Luteolin Induces Growth Arrest in Colon Cancer Cells Through Involvement of Wnt/β-Catenin/GSK-3βSignaling

Esophageal Cancer

1. Luteolin inhibits cell proliferation and induces cell apoptosis via down regulation of mitochondrial membrane potential in esophageal carcinoma cells EC1and KYSE450

2. Luteolin Induced-growth Inhibition and Apoptosis of Human Esophageal Squamous Carcinoma Cell Line Eca109 Cells in vitro


1. Luteolin, a novel p90 ribosomal S6 kinase inhibitor, suppresses proliferation and migration in leukemia cells

Liver Cancer

1. Luteolin Promotes Cell Apoptosis by Inducing Autophagy in Hepatocellular Carcinoma

2. Luteolin induces apoptosis in mouse liver cancer cells through ROS mediated pathway: A mechanistic investigation

3. Luteolin and sorafenib combination kills human hepatocellular carcinoma cells through apoptosis potentiation and JNK activation

4. Evaluation of Luteolin in the Prevention of N-nitrosodiethylamine-induced Hepatocellular Carcinoma Using Animal Model System

Lung Cancer

1. Luteolin Inhibits Tumorigenesis and Induces Apoptosis of Non-Small Cell Lung Cancer Cells via Regulation of MicroRNA-34a-5p

2. Anticancer effect of luteolin is mediated by downregulation of TAM receptor tyrosine kinases, but not interleukin-8,in non-small cell lung cancer cells

3. Luteolin is effective in the non-small cell lung cancer model with L858R/T790MEGF receptor mutation and erlotinib resistance

Oral Cancer

1. Chemotherapeutic effects of luteolin on radio-sensitivity enhancement and interleukin-6/signal transducer and activator of transcription 3 signaling repression of oral cancer stem cells

Prostate Cancer

1. Inhibition of ANO1 by luteolin and its cytotoxicity in human prostate cancer PC-3 cells

2. Luteolin inhibited proliferation and induced apoptosis of prostate cancer cells through miR-301

3. Gefitinib and Luteolin Cause Growth Arrest of Human Prostate Cancer PC-3 Cells via Inhibition of Cyclin G Associated Kinase and Induction of miR-630

4. Luteolin Inhibits Human Prostate Tumor Growth by Suppressing Vascular Endothelial Growth Factor Receptor 2-Mediated Angiogenesis

5. Luteolin inhibits invasion of prostate cancer PC3 cells through E-cadherin

Renal Cell Carcinoma

1. Induction of Apoptosis by Luteolin Involving Akt Inactivation in Human 786-O Renal Cell Carcinoma Cells

Skin Cancer

1. Luteolin Inhibits Protein Kinase Cε and c-Src Activities and UVB-Induced Skin Cancer

2. The Flavonoid Luteolin Increases the Resistance of Normal, but Not Malignant Keratinocytes, Against UVB-Induced Apoptosis

Stomach Cancer

1. Luteolin selectively kills STAT3 highly activated gastric cancer cells through enhancing the binding of STAT3 toSHP-1

2. Luteolin suppresses gastric cancer progression by reversing epithelial ‑mesenchymal transition via suppression of the Notch signaling pathway

3. Luteolin exerts a marked antitumor effect incMet-overexpressing patient-derived tumor xenograft models of gastric cancer

Thyroid Cancer

1. Luteolin suppresses tumor progression through lncRNA BANCR and its downstream TSHR/CCND1signaling in thyroid carcinoma